Histopathological Features and Antiviral Efficacy in Patients Over 30 Years Old with Chronic Hepatitis B in the Indeterminate Phase
Among HBeAg-negative CHB patients aged over 30 in the indeterminate phase, over half had significant liver inflamma tion or fibrosis. In addition, RBC was a protective factor for significant liver inflammation, and AST was a risk factor for significant liver inflammation and fibrosis in such patients. Notably, antiviral treatment was effective. However, long-term monitoring of HBV DNA and the occurrence of LLV and drug resistance should be conducted during treatment. Cite this article as: Ou K, Ma Y, Yuan C, et al. Histopathological Features and Antiviral Efficacy in Patients Over 30 Years Old with Chronic Hepatitis B in the Indeterminate Phase. Turk J Gastroenterol. 2026;37(2):186-195.
Authors
- Caimei Yuan
- Yujia Lu
- Ying Ma (ORCID: https://orcid.org/0000-0001-7994-1222)
- Yongfeng Yang (ORCID: https://orcid.org/0000-0002-3214-0038)
- Bin Liu (ORCID: https://orcid.org/0000-0002-9113-9694)
- Qing‐Fang Xiong (ORCID: https://orcid.org/0000-0001-6746-9389)
- Kevin Ou
- Jindong Cui (ORCID: https://orcid.org/0000-0002-6228-1085)
- Wannian Zhao
Institutions
- Nanjing University of Chinese Medicine (CN)
- Nanjing Second Hospital (CN)
Publication Details
- Journal
- The Turkish Journal of Gastroenterology
- Published
- 2025-10-03
- DOI
- https://doi.org/10.5152/tjg.2025.25138
- Primary Topic
- Hepatitis B Virus Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00