Studies of secondary metabolites from marine sponges in the laboratory of the chemistry of marine natural compounds of PIBOC FEB RAS in 2019–2023

Sea sponges are among the richest sources of biologically active compounds. Among them, terpenoids, alkaloids, polyketides, peptides, steroids, amino acids and other classes of compounds were found. They exhibit a wide range of biological activities such as cytotoxic, antitumor, antibacterial, antifungal, antiviral, anti-inflammatory, antioxidant, enzyme inhibitory and antimalarial. This review covers the structures and biological activities of secondary metabolites isolated from marine sponges in the Laboratory of the Chemistry of Marine Natural Compounds of the Pacific Institute of Bioorganic Chemistry, Far Eastern Branch of the Russian Academy of Sciences and published in 2019–2023.