EFFECT OF A COMPLEX PREPARATION PROSTIMUL ON THE IMMUNE STATUS OF PIGLETS UNDER TECHNOLOGICAL STRESS

The article describes the results of studies on the effect of a complex interferon-containing drug Prostimul on the immune status and relative level of gene expression of the immune status of piglets under technological stress associated with weaning. Two groups of piglets – experimental and control, participated in the study. The piglets of the experimental group were administered the drug Prostimul at a dose of 1.0 cm 3 per 10 kg of live weight twice with an interval of 48 hours. The blood from animals of each group, sampled 12 hours after the second administration of the drug Prostimul, immediately at weaning, and 48 hours later, served as the material for laboratory tests. The obtained results indicate that the drug Prostimul promotes the levelling of negative effects of technological stress on the immune status of piglets at the weaning period, which is manifested by the increase in the number of T- and B-lymphocytes, FAL, FCH, FI, LASC, vol. IG in piglets of the experimental group, as well as an increase in the relative level of expression of genes responsible for immunity.