Efficacy of progesterone nano cream (ProSync- NC) on oestrus induction and fertility outcomes in postpartum crossbred dairy cows

This study aimed to evaluate the efficacy of progesterone nano cream (PNC) to induce oestrus and conception rate in crossbred dairy cows. Twenty four crossbred dairy cows were randomly divided into two groups on day 60 postpartum on the basis of presence or absence of corpus luteum viz. with CL and without CL, each group was further divided into treatment and control, with six animals in each subgroup. On Day 0 (day 60 postpartum) in treatment animals (group1- with CL and group 2- without CL) PNC was applied on depilated skin of forelimb below knee and secured with an adhesive and water resistant bandage. On day 6, Inj. Cloprostenol 500 μg (IM) was administered and on day 7, PNC bandage was removed. Control animals (group 3- with CL and 4- without CL) were observed over a period of 21 days from day 60 postpartum without any treatment. The oestrus induction response of group 1 and 2 was 100 and 83.33 per cent, respectively. The interval from PNC removal to induced oestrus was significantly (p