On the asymptotic validity of confidence sets for linear functionals of solutions to integral equations

This paper examines the construction of confidence sets for parameters defined as linear functionals of a function of [Formula: see text] and [Formula: see text] whose conditional mean given [Formula: see text] and [Formula: see text] equals the conditional mean of another variable [Formula: see text] given [Formula: see text] and [Formula: see text]. Many estimands of interest in causal inference can be expressed in this form, including the average treatment effect in proximal causal inference and treatment effect contrasts in instrumental variable models. We derive a necessary condition for a confidence set to be uniformly valid over a model that allows for the dependence between [Formula: see text] and [Formula: see text] given [Formula: see text] to be arbitrarily weak. We show that, for any such confidence set, there must exist some laws in the model under which, with high probability, the confidence set has a diameter greater than or equal to the diameter of the parameter's range. In particular, consistent with the weak instrument literature, Wald confidence intervals are not uniformly valid over the aforementioned model when the parameter's range is infinite. Furthermore, we argue that inverting the score test, a successful approach in that literature, generally fails for the broader class of parameters considered here. We present a method for constructing uniformly valid confidence sets when all variables, but possibly [Formula: see text], are binary, discuss its limitations and emphasize that developing valid confidence sets for the class of parameters considered here remains an open problem.

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Publication Details

Journal
Biometrika
Published
2025-01-01
DOI
https://doi.org/10.1093/biomet/asaf067
Primary Topic
Industrial and Mining Safety
Type
article
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article

On the asymptotic validity of confidence sets for linear functionals of solutions to integral equations

Ezequiel Smucler, Andrea Rotnitzky, James M. Robins
Biometrika
Industrial and Mining Safety
article

On the asymptotic validity of confidence sets for linear functionals of solutions to integral equations

Ezequiel Smucler, Andrea Rotnitzky, James M. Robins
article en

Abstract

This paper examines the construction of confidence sets for parameters defined as linear functionals of a function of [Formula: see text] and [Formula: see text] whose conditional mean given [Formula: see text] and [Formula: see text] equals the conditional mean of another variable [Formula: see text] given [Formula: see text] and [Formula: see text]. Many estimands of interest in causal inference can be expressed in this form, including the average treatment effect in proximal causal inference and treatment effect contrasts in instrumental variable models. We derive a necessary condition for a confidence set to be uniformly valid over a model that allows for the dependence between [Formula: see text] and [Formula: see text] given [Formula: see text] to be arbitrarily weak. We show that, for any such confidence set, there must exist some laws in the model under which, with high probability, the confidence set has a diameter greater than or equal to the diameter of the parameter's range. In particular, consistent with the weak instrument literature, Wald confidence intervals are not uniformly valid over the aforementioned model when the parameter's range is infinite. Furthermore, we argue that inverting the score test, a successful approach in that literature, generally fails for the broader class of parameters considered here. We present a method for constructing uniformly valid confidence sets when all variables, but possibly [Formula: see text], are binary, discuss its limitations and emphasize that developing valid confidence sets for the class of parameters considered here remains an open problem.

BiometrikaVol. 112(4)
Harvard University (US), University of Washington (US), Cancer Research And Biostatistics (US), Universitat Ramon Llull (ES)
Openalex Percentile: Top 66%
Industrial and Mining Safety
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On the asymptotic validity of confidence sets for linear functionals of solutions to integral equations — Ezequiel Smucler, Andrea Rotnitzky, et al. · Biometrika (2025) | TGRS Research Map | TGRS