EGR3 Inhibits Tumor Progression by Inducing Schwann Cell‐Like Differentiation (Adv. Sci. 34/2024)
Schwann Cell‐Like Differentiation From left to right, the image shows lipid nanoparticles with CD86‐P2A‐EGR3 mRNA entering a melanoma cell, reprogramming it into a Schwann cell‐like melanoma cell with long protrusions, reduced migration, and CD86 receptor expression. The reprogrammed cell then recruits immune cells, enhancing immune infiltration, T cell expansion, and effective tumor control. More details can be found in article number 2400066 by Tao Sun and co‐workers. [Image: see text]
Authors
- Tao Sun (ORCID: https://orcid.org/0000-0002-8962-2193)
- Xiu Huang (ORCID: https://orcid.org/0000-0002-1368-4080)
- Caihong Chen (ORCID: https://orcid.org/0009-0003-9320-4490)
- Heng Zhang (ORCID: https://orcid.org/0000-0002-9003-9624)
- Yingying Li (ORCID: https://orcid.org/0000-0003-3938-4761)
- Zhiyang Li (ORCID: https://orcid.org/0000-0002-5481-3985)
- Huijuan Liu (ORCID: https://orcid.org/0000-0002-8096-7005)
- Xin‐ying Wu
- Jingxia Han
- Yi‐nan Li
- Yang Chen (ORCID: https://orcid.org/0000-0002-9772-8692)
Publication Details
- Journal
- Advanced Science
- Published
- 2024-09-01
- DOI
- https://doi.org/10.1002/advs.202470207
- Primary Topic
- Neuroblastoma Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00