Peculiarities of the effect of manganese and cadmium ions on the properties of liposomes from lecithin

The features of the influence of divalent cadmium and manganese ions on the ability of lecithin to form aggregates in water medium, its ζ-potential, and the state of the lipid peroxidation processes have been studied. The methods used were TLC, dynamic light scattering, and processing of UV spectra using the Gauss method. It was revealed that cadmium ions accelerate the processes of lipid oxidation in liposomes, and manganese ions inhibit them. At the same time, cadmium ions, as opposed to manganese ions, require more period to interact with the membrane structure of liposomes. The data obtained and the analysis of the literature allow us to conclude that the cadmium and manganese ions present in the solution influence the spontaneous aggregation of lecithin and participate at different stages of the oxidation process in accordance with their biological activity when entering the body.