Evaluation of the Effect of Chia (Salvia hispanica) Seeds Extract  in modulating Fertility Potential, Injury and Histopathological  Alterations Induced by Fenitrothion in Male Rats

The study aimed to evaluate the effect of chia seed extract as a protective against fenitrothion toxicity in male rats. Total forty rats were divided into four groups: the first group was the control group (no treatment), the second group was treated with Chia (Salvia hispanica) seeds at a dose of 400 mg/kg body weight daily, the third group was treated with Fenitrothion at a dose of 100 mg/kg body weight, and the fourth group was treated with both Chia (Salvia hispanica) seeds and fenitrothion. Rats were treated orally for three weeks daily. The results showed changes in the concentration of hormones and sperm characteristics in rats treated with fenitrothion compared to the control group. The exposure to fenitrothion has a noticeable toxic effect on rats through measuring some vital indicators. The role of chia seed extract in reducing lipid oxidation and improving the antioxidant defense system has been proven. We conclude from the above that exposure to fenitrothion has a noticeable toxic effect on rats through measuring some vital indicators, The role of chia seed extract in reducing lipid oxidation and improving the antioxidant defense system has been proven