8292638 How Incidental Exposure to Ethylene Oxide Resulted in Air Measurements, Biomonitoring and Strong Collaboration Between Occupational Hygienist and Occupational Physician

<h3>Objective</h3> Accidentally, a warehouse company was alerted to the potential exposure to ethylene oxide. In response, the company took immediate action in accordance with the measures outlined in the occupational hygiene strategy. However, to what extent has this been an issue in the past? By conducting air measurements and taking blood samples, the company aims to find answers to alleviate concerns among employees. <h3>Material and Methods</h3> In total, over 55 personal and stationary air samples were conducted. Blood samples were taken both before and after control measures from nearly all employees to determine the adduct N-(2-hydroxyethyl)valine (HEV) as a measure of historical exposure. Additionally, a occupational physician was involved in the process to conduct health assessments. <h3>Results</h3> The results of the air measurements indicate that the exposure for warehouse employees can be considered controlled according to the criteria from NEN-EN 689 (UTL95,70 of 37.3 μg/m3). However, the results of the blood samples regarding historical exposure show that 75% of the samples contained a concentration approximately equal to the limit value for EtO in air. For 95% of the most highly exposed employees, there is an additional risk of developing cancer. In two employees from this group, a concentration above the prohibition level was found. The results of the blood samples taken after 4 months show a significant decrease (&gt;60%) in the concentration of HEV. An overview of the diagnosed health complaints will be presented during the presentation. <h3>Conclusions</h3> Currently, there is no longer a health risk for warehouse employees. However, employees were exposed to health-damaging concentrations of EtO in the past. The question remains how it is possible that the company was unaware of potential exposure. We will elaborate on which lessons can be learned for other companies in this sector and highlight the importance of the intensive collaboration between the hygienist and physician.