8287710 CAREX Canada: perspectives on the use of population-based exposure surveillance programs for use in risk or burden estimates

<h3>Objective</h3> CAREX Canada is a longstanding program of research that develops and disseminates estimates of the number of workers exposed to carcinogens. The objective of this talk is to offer a Canadian perspective on using population-level exposure estimates, with particular consideration of how these estimates have been used in Canadian risk and burden studies, and some of the benefits and limitations of these approaches. <h3>Material and Methods</h3> CAREX Canada began as a pilot program in 2003, based on methods developed in EU-based CAREX programs in the early 1990s. In 2008, it was supported by the cancer research arm of the Canadian government as a national program of research, who continue to fund it to this day. Using a mixed methods approach including key informant interviews, exposure measurement databases, and expert opinion, along with detailed census information, estimates have been generated for 2006 and 2016, with estimates for 2021 due to be released this fiscal year. <h3>Results</h3> Estimates of occupational exposure have been generated for &gt;50 agents, many of which also have estimates of exposure level. They have contributed to many policy impacts, including a federal ban on asbestos in 2018 and a shifting of provincial approaches to reduce outdoor workers’ sun exposure. They have also been used in the national Burden of Occupational Cancer study for Canada, in addition to a number of epidemiological studies where CAREX estimates were converted into job exposure matrices. <h3>Conclusion</h3> CAREX Canada estimates have been used for policy influence and change, to raise awareness of occupational cancer for workers, their employers, and society more broadly, and have been translated into job exposure matrices for use in epidemiological investigators. While data like these are extremely important for understanding the extent of occupational cancer and disease, it is important to consider the limitations of these approaches.