8000001 Do psychosocial working conditions moderate the association between menopausal symptoms and presenteeism? The lifelines cohort study

<h3>Objective</h3> Given the high prevalence of menopausal symptoms and their potential impact on work functioning, understanding the role of work conditions may inform targeted workplace interventions. Therefore, this study aims to examine the association between menopausal symptoms and presenteeism, and whether it is moderated by psychosocial working conditions. <h3>Methods</h3> Data were used from 16,157 working women participating in the Lifelines Cohort Study, who completed a questionnaire on menopause and work. Current study included 9,269 employed women aged 40–67 years who were in the peri- (n = 1,883) or postmenopausal stage (n = 7,386). Menopausal symptoms were measured with the Greene Climacteric Scale and presenteeism with the Work Productivity and Activity Impairment questionnaire. Psychosocial work conditions included job demands, work pace, influence at work, job insecurity, social support from colleagues, social support from supervisor measured by the COPSOQ, and autonomy at work measured by the VBBA. Moderation by each psychosocial work condition was tested using linear regression models with an interaction term and adjusted for demographic factors, lifestyle factors, working hours, and chronic diseases. For significant interactions (p &lt; 0.10), we conducted stratified analyses. <h3>Results</h3> Preliminary results indicate that menopausal symptoms were associated with increased presenteeism (β =12.1, 95% CI 11.6-12.7). The association between menopausal symptoms and increased presenteeism was significantly moderated by job demands, job insecurity, and autonomy. Stratified analyses showed that stronger associations between menopausal symptoms and increased presenteeism were observed among women with high job demands and insecurity, and low autonomy at work. <h3>Conclusion</h3> Preliminary findings show that menopausal symptoms are associated with increased presenteeism, which is stronger among women with high job demands, high job insecurity and low autonomy. If confirmed, these psychosocial work factors should be addressed in interventions aimed at supporting women’s health and sustainable employability during midlife.