Sustainable Green Synthesis and Evaluation of Antimicrobial Potential of Silver Nanoparticles prepared from the Stem Extract of Mangifera indica: A Biogenic Approach

The present study demonstrates the production of silver nanoparticles (SNPs) utilizing an aqueous extract from the stem of Mangifera indica and their application as an antimicrobial agent against diverse pathogenic microorganisms. The presence of a dark brown colour visually supported SNP biosynthesis, which was also confirmed by UV spectra at 450 nm. FE-SEM (Field Emission Electron Scanning Electron Microscopy) examinations revealed the nanoparticles' spherical to oval shape, while EDX (Energy-Dispersive X-ray) research proved their elemental makeup. XRD research revealed that SSNPs (Stem SNPs) have a face-centred cubic crystalline structure with an average size of 10 nm. FT-IR research demonstrated that the bio-functional groups included in the plant extract stimulate the production of SNPs while also promoting the capping and stabilization of the SNPs. The phytochemical examination revealed the presence of bioactive compounds. The SSNPs had more antibacterial activity than antifungal activity. A single-factor ANOVA was used for statistical analysis and p < 0.05 was considered statistically significant. The study's findings indicate that many naturally occurring bioactive chemicals in plant extracts may be usefully employed in nanoparticle-making. In contrast to traditional antibiotics, this study demonstrated an effective, practical and repeatable approach for manufacturing inexpensive, environmentally benign and long-lasting plant-mediated SNPs and their use as powerful antimicrobial agents against pathogenic microorganisms.