130246 A natural history study of paediatric myelin oligodendrocyte glycoprotein antibody-associated disease related optic neuritis (MOGAD-ON)

In our cohort, the appearance, evolution, and resolution of DWP lesions occurred around episodes of uveitis activity and resolution.We hypothesise that DWP in active uveitis patients may be a marker of underlying disease activity, although the precise pathophysiological mechanism is not yet fully understood.This association could provide a novel clinical sign in the monitoring of uveitis in some children.

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Publication Details

Published
2025-10-01
DOI
https://doi.org/10.1136/bmjophth-2025-biposa.4
Primary Topic
Peripheral Neuropathies and Disorders
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article
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article

130246 A natural history study of paediatric myelin oligodendrocyte glycoprotein antibody-associated disease related optic neuritis (MOGAD-ON)

Joshua Harvey, Ming Lim, Ailsa Ritchie, Jon O. Cleary et al.
Peripheral Neuropathies and Disorders
article

130246 A natural history study of paediatric myelin oligodendrocyte glycoprotein antibody-associated disease related optic neuritis (MOGAD-ON)

Joshua Harvey, Ming Lim, Ailsa Ritchie, Jon O. Cleary, Thomas Rossor
article en

Abstract

In our cohort, the appearance, evolution, and resolution of DWP lesions occurred around episodes of uveitis activity and resolution.We hypothesise that DWP in active uveitis patients may be a marker of underlying disease activity, although the precise pathophysiological mechanism is not yet fully understood.This association could provide a novel clinical sign in the monitoring of uveitis in some children.

Guy's and St Thomas' NHS Foundation Trust (GB)
Openalex Percentile: Top 60%
Peripheral Neuropathies and Disorders
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