Oxidative Imbalance in Conversion Disorder: Evidence from Thiol-Disulphide Homeostasis Disruption

Our findings indicate that patients with Conversion Disorder may show oxidative imbalance together with elevated CRP levels, supporting the notion that redox and inflammatory pathways could be involved in the disorder's pathophysiology. Thiol/disulfide homeostasis and CRP might therefore represent peripheral biomarkers of interest, although the cross-sectional, single-center design and the restricted set of biomarkers assessed call for cautious interpretation of these results. This is the first study to concurrently evaluate TDH and CRP in CD.

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Publication Details

Journal
Neuropsychiatric Disease and Treatment
Published
2025-10-01
DOI
https://doi.org/10.2147/ndt.s531147
Primary Topic
Psychosomatic Disorders and Their Treatments
Type
article
Field-Weighted Citation Impact
0.00

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article

Oxidative Imbalance in Conversion Disorder: Evidence from Thiol-Disulphide Homeostasis Disruption

Hasan Büyükaslan, Mustafa Sever, İbrahim Halil Yasak, İsmail Koyuncu et al.
Neuropsychiatric Disease and Treatment
Psychosomatic Disorders and Their Treatments
article

Oxidative Imbalance in Conversion Disorder: Evidence from Thiol-Disulphide Homeostasis Disruption

Hasan Büyükaslan, Mustafa Sever, İbrahim Halil Yasak, İsmail Koyuncu, Hüseyin Gürbüz, Mehmet Aşoğlu, Şenay Koçakoğlu
article en

Abstract

Our findings indicate that patients with Conversion Disorder may show oxidative imbalance together with elevated CRP levels, supporting the notion that redox and inflammatory pathways could be involved in the disorder's pathophysiology. Thiol/disulfide homeostasis and CRP might therefore represent peripheral biomarkers of interest, although the cross-sectional, single-center design and the restricted set of biomarkers assessed call for cautious interpretation of these results. This is the first study to concurrently evaluate TDH and CRP in CD.

Neuropsychiatric Disease and TreatmentVol. Volume 21
Izmir University (TR), Sağlık Bilimleri Üniversitesi (TR), Harran University (TR)
Harran Üniversitesi
Openalex Percentile: Top 67%
Psychosomatic Disorders and Their Treatments
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