Preterm birth in women with psoriatic arthritis: what are the risks and risk factors? A collaborative cohort study from Sweden, Denmark and Norway
We identified an 80% increased risk of preterm birth in PsA pregnancies compared with control pregnancies. Antirheumatic combination therapy during and high disease load before pregnancy constituted risk factors. Discontinuing bDMARD treatment in early pregnancy further increased the risk. Our findings support that a subgroup of PsA pregnancies should be considered high-risk pregnancies.
Authors
- Anne Emilie Pape Secher (ORCID: https://orcid.org/0000-0002-0541-0733)
- Karin Hellgren (ORCID: https://orcid.org/0000-0001-7149-0973)
- Brigitte Michelsen (ORCID: https://orcid.org/0000-0003-0103-2840)
- Ane Lilleøre Rom (ORCID: https://orcid.org/0000-0003-2474-2677)
- Katarina Remaeus (ORCID: https://orcid.org/0000-0003-0971-132X)
- Merete Lund Hetland (ORCID: https://orcid.org/0000-0003-4229-6818)
- Bente Glintborg (ORCID: https://orcid.org/0000-0002-8931-8482)
- Fredrik Granath
Institutions
- University of Copenhagen (DK)
- University of Southern Denmark (DK)
- Copenhagen University Hospital (DK)
- Rigshospitalet (DK)
- Karolinska Institutet (SE)
- Sørlandet Hospital Arendal (NO)
- Diakonhjemmet Hospital (NO)
- Sørlandet Sykehus (NO)
Publication Details
- Journal
- RMD Open
- Published
- 2025-10-01
- DOI
- https://doi.org/10.1136/rmdopen-2025-005614
- Primary Topic
- Pregnancy and Medication Impact
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Gigtforeningen
- NordForsk
- Reumatikerförbundet
- Foundation for Research in Rheumatology