<i>O</i> -GlcNAc transferase promotes immune evasion and immunotherapy resistance in uterine corpus endometrial cancer by targeting the glucocorticoid receptor

Our findings reveal cross-talk between the HBP, steroid hormone pathway, and tumor immune evasion, and suggest potential strategies for sensitizing UCEC to immunotherapy.

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Publication Details

Journal
Journal for ImmunoTherapy of Cancer
Published
2025-10-01
DOI
https://doi.org/10.1136/jitc-2025-011479
Citations
1
Primary Topic
Immune Cell Function and Interaction
Type
article
Field-Weighted Citation Impact
0.80

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article

O -GlcNAc transferase promotes immune evasion and immunotherapy resistance in uterine corpus endometrial cancer by targeting the glucocorticoid receptor

Ke‐Qiong Deng, Jingjing Wang, Xuemin Song, Ying Zhu et al.
1 citations
Journal for ImmunoTherapy of Cancer
Immune Cell Function and Interaction
0.80
article

O -GlcNAc transferase promotes immune evasion and immunotherapy resistance in uterine corpus endometrial cancer by targeting the glucocorticoid receptor

Ke‐Qiong Deng, Jingjing Wang, Xuemin Song, Ying Zhu, Shuo Rong, Yang Xie, Zhibing Lu, Huanhuan Cai, Chao Xu, Li Liu, Hao Zeng, Shi Liu, Li Zhou, Xiangtai Zeng, Min-chao Dai
article en
1 citations

Abstract

Our findings reveal cross-talk between the HBP, steroid hormone pathway, and tumor immune evasion, and suggest potential strategies for sensitizing UCEC to immunotherapy.

Journal for ImmunoTherapy of CancerVol. 13(10)
Central South University (CN), Wuhan University (CN), Wuhan Institute of Virology (CN), Zhongnan Hospital of Wuhan University (CN), Stomatology Hospital (CN), First Affiliated Hospital of Gannan Medical University (CN), Second Xiangya Hospital of Central South University (CN), Hainan 301 Hospital (CN)
National Natural Science Foundation of China, Natural Science Foundation of Hubei Province, Wuhan University, Science and Technology Department of Hubei Province, National Key Research and Development Program of China, Fundamental Research Funds for the Central Universities
Openalex Percentile: Top 23%
Immune Cell Function and Interaction
0.80
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