Retrospective evaluation of correlation of ABO blood groups among patients with head and neck cancer
Head and neck cancer (HNC) is a multifactorial disease influenced by genetic and environmental factors. This retrospective case-control study examined the relationship between ABO blood groups and the risk of HNC in 542 patients and 1084 controls. Blood group A was significantly associated with increased HNC risk (OR = 1.42, p = 0.004), particularly for oral cavity cancers, while blood group O showed a borderline protective effect. No significant associations were noted for blood groups B or AB. Thus, we show ABO blood group may play a role in HNC susceptibility.
Authors
- Aleya Khatun
- Jugajyoti Pathi (ORCID: https://orcid.org/0009-0005-8906-0097)
- Shobhit Saxena
- Parbodh Chander Sharma (ORCID: https://orcid.org/0000-0002-5783-7480)
- Supriya Raghav
- Shweta Hegde
- Miral Mehta
- Santoshkumar Kotnoor
Institutions
- Sant Gadge Baba Amravati University (IN)
- Manubhai Patel Dental College and Hospital (IN)
- Kothiwal Dental College and Research Centre (IN)
- Chhattisgarh Dental College & Research Institute (IN)
- Sankalchand Patel University (IN)
- Karnavati University
- KIIT University (IN)
- Kamineni Institute of Dental Sciences (IN)
Publication Details
- Journal
- Bioinformation
- Published
- 2025-09-30
- DOI
- https://doi.org/10.6026/973206300213181
- Primary Topic
- Blood groups and transfusion
- Type
- article
- Field-Weighted Citation Impact
- 0.00