Cardiovascular risk factors and life expectancy in India: A retrospective study

Cardiovascular disease (CVD) remains the leading cause of adult mortality in India. Hence, we retrospectively analyzed electronic records of 4,812 adults from two tertiary hospitals to quantify major CVD risk factors and their association with survival and estimated remaining life expectancy (LE) at age 40 using Chiang's abridged life table with Sample Registration System (SRS) background rates. Hypertension, diabetes, dyslipidemia, smoking and obesity were frequent (≥20% each). Adjusted Cox models showed stepwise higher mortality with increasing risk-factor count (≥3 vs 0: HR 1.92; 95% CI 1.49-2.48; p<0.001). Estimated LE at 40 declined from 39.6 (0 factors) to 33.2 years (≥3). Findings underscore intensified primary prevention.

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Published
2025-09-30
DOI
https://doi.org/10.6026/973206300213242
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Cardiovascular Health and Risk Factors
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Cardiovascular risk factors and life expectancy in India: A retrospective study

Heena Tiwari, Daisy Bacchani, Rahul Tiwari, Prashant Kumar et al.
Bioinformation
Cardiovascular Health and Risk Factors
article

Cardiovascular risk factors and life expectancy in India: A retrospective study

Heena Tiwari, Daisy Bacchani, Rahul Tiwari, Prashant Kumar, PASSONI Luiz Fernando C., Venkata N. Bhavani Penmathsa
article en

Abstract

Cardiovascular disease (CVD) remains the leading cause of adult mortality in India. Hence, we retrospectively analyzed electronic records of 4,812 adults from two tertiary hospitals to quantify major CVD risk factors and their association with survival and estimated remaining life expectancy (LE) at age 40 using Chiang's abridged life table with Sample Registration System (SRS) background rates. Hypertension, diabetes, dyslipidemia, smoking and obesity were frequent (≥20% each). Adjusted Cox models showed stepwise higher mortality with increasing risk-factor count (≥3 vs 0: HR 1.92; 95% CI 1.49-2.48; p<0.001). Estimated LE at 40 declined from 39.6 (0 factors) to 33.2 years (≥3). Findings underscore intensified primary prevention.

BioinformationVol. 21(09)
Siddhartha Medical College (IN), Sarojini Naidu Medical College (IN), RKDF University (IN), Rajendra Institute of Medical Sciences (IN), Index Medical College, Hospital & Research Centre (IN)
Openalex Percentile: Top 58%
Cardiovascular Health and Risk Factors
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