Comparison of transient elastography data among diabetic and non-diabetics: A study from teritiary health care centre in Kerala, India

Non-alcoholic fatty liver disease (NAFLD) is a common metabolic disorder with a strong association to type 2 diabetes mellitus (T2DM). Therefore, it is of interest to compare transient elastography findings among diabetic and non-diabetic individuals in a tertiary healthcare setting in Kerala. A total of 220 participants were assessed, of which 73 were diabetic and liver stiffness was measured using FibroScan®. Diabetic patients exhibited significantly higher mean fibrosis scores compared to non-diabetic patients (14.39 ± 14.42 vs. 8.14 ± 7.83, p=0.000). Thus, we show diabetes as a major predictor of advanced liver fibrosis, underscoring the need for early detection and targeted interventions in high-risk populations.

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Published
2025-09-30
DOI
https://doi.org/10.6026/973206300213218
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Cardiovascular Health and Disease Prevention
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article
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Comparison of transient elastography data among diabetic and non-diabetics: A study from teritiary health care centre in Kerala, India

Senthilvel Vasudevan, Rosemary Thomas, Sneha M Nair, Sameena Sheeba Safarullah et al.
Bioinformation
Cardiovascular Health and Disease Prevention
article

Comparison of transient elastography data among diabetic and non-diabetics: A study from teritiary health care centre in Kerala, India

Senthilvel Vasudevan, Rosemary Thomas, Sneha M Nair, Sameena Sheeba Safarullah, Rohith Kunnath, Mark Anil Mansingh
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Abstract

Non-alcoholic fatty liver disease (NAFLD) is a common metabolic disorder with a strong association to type 2 diabetes mellitus (T2DM). Therefore, it is of interest to compare transient elastography findings among diabetic and non-diabetic individuals in a tertiary healthcare setting in Kerala. A total of 220 participants were assessed, of which 73 were diabetic and liver stiffness was measured using FibroScan®. Diabetic patients exhibited significantly higher mean fibrosis scores compared to non-diabetic patients (14.39 ± 14.42 vs. 8.14 ± 7.83, p=0.000). Thus, we show diabetes as a major predictor of advanced liver fibrosis, underscoring the need for early detection and targeted interventions in high-risk populations.

BioinformationVol. 21(09)
Northern General Hospital (GB), T. D. Medical College (IN), Indian Institute of Technology Palakkad (IN), Kerala Institute of Medical Sciences (IN), Institute of Medical Sciences (IN), Karnataka Institute of Medical Sciences (IN)
Openalex Percentile: Top 58%
Cardiovascular Health and Disease Prevention
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