Single‐cell RNA sequencing reveals cell immune status and dysregulated monocytes in patients with myasthenia gravis
Our study provides a comprehensive cell landscape for patients with MG, identifies two dysregulated monocytes, elucidates the inflammation status and offers a new perspective on understanding the aetiology of functional cure and potential therapeutic strategies for patients with MG.
Authors
- Bijun Zhang (ORCID: https://orcid.org/0000-0002-7596-3376)
- Xintao Wu (ORCID: https://orcid.org/0000-0002-2823-3063)
- Yuting Jin (ORCID: https://orcid.org/0000-0002-4336-2680)
- Jianhua Feng (ORCID: https://orcid.org/0000-0002-5849-407X)
- Xin Lin (ORCID: https://orcid.org/0000-0002-1563-8168)
- Chudi Zhang (ORCID: https://orcid.org/0000-0002-0839-3908)
- Ye Wang (ORCID: https://orcid.org/0000-0002-2608-368X)
- Yuting Lou
- Pu Miao (ORCID: https://orcid.org/0000-0001-5165-2613)
- Yufan Guo (ORCID: https://orcid.org/0000-0002-1527-0383)
- Yu Gu (ORCID: https://orcid.org/0000-0003-3825-6557)
Institutions
- Second Affiliated Hospital of Zhejiang University (CN)
- Zhejiang University (CN)
Publication Details
- Journal
- Clinical & Translational Immunology
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1002/cti2.70052
- Primary Topic
- Myasthenia Gravis and Thymoma
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Science and Technology Department of Zhejiang Province