Cross-sectional study on ethnic variations in gut microbiome diversity and hypertension severity

Stool samples were analyzed using 16S rRNA sequencing and blood pressure measurements were categorized per AHA guidelines. Hence, 130 adults from three ethnic groups to assess differences in gut microbiome diversity and their association with hypertension severity were studied. Significant ethnic variations were observed in microbial composition, particularly in Firmicutes-to-Bacteroidetes ratios. Greater microbial diversity was associated with lower hypertension severity in certain ethnicities. Thus, we show ethnic-specific microbiome patterns may influence hypertension outcomes.

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Journal
Bioinformation
Published
2025-09-30
DOI
https://doi.org/10.6026/973206300213043
Primary Topic
Gut microbiota and health
Type
article
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article

Cross-sectional study on ethnic variations in gut microbiome diversity and hypertension severity

Tina Patel, Rajput Nixitsinh Arvindssinh, Madan Karthik Raj MR
Bioinformation
Gut microbiota and health
article

Cross-sectional study on ethnic variations in gut microbiome diversity and hypertension severity

Tina Patel, Rajput Nixitsinh Arvindssinh, Madan Karthik Raj MR
article en

Abstract

Stool samples were analyzed using 16S rRNA sequencing and blood pressure measurements were categorized per AHA guidelines. Hence, 130 adults from three ethnic groups to assess differences in gut microbiome diversity and their association with hypertension severity were studied. Significant ethnic variations were observed in microbial composition, particularly in Firmicutes-to-Bacteroidetes ratios. Greater microbial diversity was associated with lower hypertension severity in certain ethnicities. Thus, we show ethnic-specific microbiome patterns may influence hypertension outcomes.

BioinformationVol. 21(09)
Sir Sayajirao General Hospital Medical College (IN)
Openalex Percentile: Top 75%
Gut microbiota and health
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