A STUDY OF PHYTOCHEMICAL SCREENING AND ANTICONVULSANT ACTIVITY OF PALM LEAVES PHOENIX DACTYLIFERA
The present study aimed to evaluate the anticonvulsant activity of leaves plant extractof phoenix dactylifera L. using PTZ-induced seizure models. The leaves of date-palmwas subjected to extraction in methanol (99.9%). The phytochemical screening of theextract revealed the presence the alkaloids, falvonoids, glycosides, saponin, steroids,tannins, and gum. The methanolic activity of the extract of the leaves of date-palmwas observed for their anticonvulsant activity induced by pentylenetetrazole test usingAlbino Westar rats. The extract in doses (100, 200, 400 mg/kg, intraperitoneal) for 5successive days. Complete protection against Tonic–clonic convulsion and mortalitywere observed. We concluded that phoenix dactilifera leaves pose anticonvulsantproperties and further investigation and phytochemical screening are needed to findout the much action.
Authors
- S. A. A. Amer
- Hanan M. Diab
- Naisreen A. El-karshin
- Nawara O. Abaurawia
- Nawal O. Abaurawia
Institutions
- Misurata University (LY)
- Libyan Academy (LY)
Publication Details
- Journal
- Misurata Medical Sciences Journal
- Published
- 2025-06-24
- DOI
- https://doi.org/10.36602/mmsj/2025.n09.03
- Primary Topic
- Date Palm Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00