Kocuria kristinae blood infection in preterm neonates associated with peripherally inserted central catheter: a case report

Background: Kocuria kristinae (K. kristinae) is a gram-positive bacteria generally regarded as non-pathogenic, although it has surfaced as a possible opportunistic pathogen, especially in immunocompromised persons and neonates. Therefore in this study aims to know K. kristinae blood infection in preterm neonates associated with peripherally inserted central catheters. Case Presentation: This case report describes a K. kristinae infection in a male preterm neonate born at 31 weeks, presenting with low birth weight and other comorbidities, including respiratory distress and possible early-onset sepsis. Notwithstanding initial antibiotic treatment with ampicillin and gentamicin, the patient exhibited deteriorating symptoms, culminating in the detection of K. kristinae by VITEK 2 COMPACT following the use of many invasive devices. The infection did not respond to meropenem. However, therapy with vancomycin resulted in substantial clinical improvement. The patient was discharged after 44 days, with complete recovery observed during follow-up. Conclusion: This instance highlights the necessity for vigilance regarding K. kristinae as a possible infection in newborns, especially those with invasive equipment. It underscores the significance of suitable antibiotic treatment, with vancomycin demonstrating efficacy.