Effects of Lipid Profiles and Vitamin D Levels on the Degree of Fatty Liver in Children with Non-Alcoholic Fatty Liver Disease

Aim: The aim of the study was to compare vitamin D, triglyceride and cholesterol levels of hepatosteatosis patients with healthy control patients. Material and Methods: Ninety-nine patients with hepatosteatosis and healthy control patients were included in our study retrospectively. The patients included in the study were patients who applied to the pediatric gastroenterology outpatient clinic between 2020 and 2023. Results: A total of 99 patients, 47 (47.5%) with hepatosteatosis and 52 (52.5%) in the control group, were included in our study. Mean ALT values were 35.2 ± 19.5 and 28.3 ± 13.0 in the hepatosteatosis and control groups, respectively (P= 0.039). Mean triglyceride (136 ± 28 vs 125 ± 24; P= 0.042) and cholesterol (165 ± 20 vs 154 ± 20; P= 0.010) levels were higher in the hepatosteatosis group than in the control group and the result was found to be significantly different. Mean vitamin D levels did not differ between the groups. Vitamin D deficiency was found to be high in both groups, but no difference was analyzed between the groups (72.3% vs 61.5%; P= 0.491). Conclusion: Triglyceride and cholesterol levels were found to be higher in patients with hepatosteatosis. Fasting blood glucose is higher in the hepatosteatosis group. Based on these results and the literature, patients with hepatosteatosis pose a risk for important diseases such as metabolic syndrome and cardiovascular diseases such as atherosclerosis in the following years.