<b>Agreement between a point-of-care analyzer and a reference laboratory analyzer for plasma phenobarbital quantification in dogs and cats</b>

This study suggests that caution should be exercised when using both analyzers interchangeably in clinical practice. In most cases from this study's population, the POC analyzer yielded higher phenobarbital concentrations. Clinicians should consider these discrepancies and interpret phenobarbital levels with caution, especially when switching analyzers during therapeutic drug monitoring. Further research is warranted to explore the causes of these differences and assess their clinical relevance in a broader population.

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Publication Details

Journal
Open Veterinary Journal
Published
2025-01-01
DOI
https://doi.org/10.5455/ovj.2025.v15.i9.76
Primary Topic
Veterinary Pharmacology and Anesthesia
Type
article
Field-Weighted Citation Impact
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article

Agreement between a point-of-care analyzer and a reference laboratory analyzer for plasma phenobarbital quantification in dogs and cats

Nicolas Van Caenegem, Grégoire Scherf
Open Veterinary Journal
Veterinary Pharmacology and Anesthesia
article

Agreement between a point-of-care analyzer and a reference laboratory analyzer for plasma phenobarbital quantification in dogs and cats

Nicolas Van Caenegem, Grégoire Scherf
article en

Abstract

This study suggests that caution should be exercised when using both analyzers interchangeably in clinical practice. In most cases from this study's population, the POC analyzer yielded higher phenobarbital concentrations. Clinicians should consider these discrepancies and interpret phenobarbital levels with caution, especially when switching analyzers during therapeutic drug monitoring. Further research is warranted to explore the causes of these differences and assess their clinical relevance in a broader population.

Open Veterinary JournalVol. 15(9)
Institut d'Électronique et des Technologies du numéRique (FR), Hôpital Nord (FR)
Openalex Percentile: Top 70%
Veterinary Pharmacology and Anesthesia
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