Network Pharmacology of Natural Polyphenols for Stroke: A Bioinformatic Approach to Drug Design
This study highlights the neuroprotective role of selected polyphenols through the PI3K/Akt pathway. Further studies are required to investigate additional molecular mechanisms between the polyphenols and their derivatives against pathological targets of Stroke.
Authors
- Ling Shing Wong (ORCID: https://orcid.org/0000-0002-5869-0804)
- T. Tamilanban (ORCID: https://orcid.org/0000-0002-3240-0645)
- Vetriselvan Subramaniyan (ORCID: https://orcid.org/0000-0002-9629-9494)
- Siew Hua Gan (ORCID: https://orcid.org/0000-0001-6470-3651)
- Arunkumar Subramanian (ORCID: https://orcid.org/0000-0002-2707-2501)
- Yuan Seng Wu (ORCID: https://orcid.org/0000-0001-5574-8049)
- Mahendran Sekar (ORCID: https://orcid.org/0000-0002-3022-6137)
- Vinoth Kumarasamy (ORCID: https://orcid.org/0000-0002-8895-1796)
- Adel Al Fatease (ORCID: https://orcid.org/0000-0002-4608-5949)
- Amrita Muralikrishnan (ORCID: https://orcid.org/0000-0002-8767-2672)
- S. Dutta (ORCID: https://orcid.org/0000-0002-1038-5608)
- M. Yasmin Begum (ORCID: https://orcid.org/0000-0002-1871-8585)
Institutions
- Monash University Malaysia (MY)
- INTI International University (MY)
- SRM Institute of Science and Technology (IN)
- University Kebangsaan Malaysia Medical Centre (MY)
- Mahsa University (MY)
- King Khalid University (SA)
- Sunway University (MY)
Publication Details
- Journal
- Advances and Applications in Bioinformatics and Chemistry
- Published
- 2025-10-01
- DOI
- https://doi.org/10.2147/aabc.s470861
- Citations
- 3
- Primary Topic
- Computational Drug Discovery Methods
- Type
- article
- Field-Weighted Citation Impact
- 4.51