USP8, USP48, BRAF and TP53 mutations in crooke cell adenoma

CCAs have slightly distinct mutational profile then other histological subtypes of cPAs. Since clinical relevance of TP53 variants in corticotroph tumors was already documented, testing toward TP53 sequence changes in patients with CCAs should be considered.

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Publication Details

Journal
Pituitary
Published
2025-10-01
DOI
https://doi.org/10.1007/s11102-025-01566-5
Citations
1
Primary Topic
Pituitary Gland Disorders and Treatments
Type
article
Field-Weighted Citation Impact
1.29

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article

USP8, USP48, BRAF and TP53 mutations in crooke cell adenoma

Paulina Kober, Artur Kowalik, Monika Pękul, Beata Joanna Mossakowska et al.
1 citations
Pituitary
Pituitary Gland Disorders and Treatments
1.29
article

USP8, USP48, BRAF and TP53 mutations in crooke cell adenoma

Paulina Kober, Artur Kowalik, Monika Pękul, Beata Joanna Mossakowska, Magdalena Szczepaniak, Grzegorz Zieliński, Natalia Rusetska, Mateusz Bujko, Maria Maksymowicz, Jacek Kunicki
article en
1 citations

Abstract

CCAs have slightly distinct mutational profile then other histological subtypes of cPAs. Since clinical relevance of TP53 variants in corticotroph tumors was already documented, testing toward TP53 sequence changes in patients with CCAs should be considered.

PituitaryVol. 28(5)
Jan Kochanowski University (PL), National Institute of Oncology (HU), Wojskowy Instytut Medycyny Lotniczej (PL), Holy Cross University (PL), The Maria Sklodowska-Curie National Research Institute of Oncology (PL)
Narodowym Centrum Nauki
Openalex Percentile: Top 15%
Pituitary Gland Disorders and Treatments
1.29
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