The Biomolecular Effects of Finasteride on Male Rat Brain during Administration and after Discontinuation
Suppression of c-Fos-related neural activity in rat brain tissue could be temporarily maximized by both type 1 and type 2 5-alpha reductase inhibition by finasteride administration, and this suppression could be relieved by the restoration of 5-alpha reductase type 1 expression after finasteride discontinuation.
Authors
- Jin Bong Choi (ORCID: https://orcid.org/0000-0003-2508-6819)
- Young Hyo Choi (ORCID: https://orcid.org/0000-0002-3602-9791)
- Seung-Ho Yang (ORCID: https://orcid.org/0000-0002-3490-1064)
- Jun Sung Koh (ORCID: https://orcid.org/0000-0001-7432-4209)
- Hee Youn Kim (ORCID: https://orcid.org/0000-0003-4149-5479)
- Dong Sup Lee (ORCID: https://orcid.org/0000-0003-0862-3205)
Institutions
- The Catholic University of Korea St. Vincent's Hospital (KR)
- The Catholic University of Korea Bucheon St. Mary's Hospital (KR)
- Catholic University of Korea (KR)
Publication Details
- Journal
- The World Journal of Men s Health
- Published
- 2025-01-01
- DOI
- https://doi.org/10.5534/wjmh.250105
- Primary Topic
- Hormonal and reproductive studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00