Magnolol Inhibits the Growth of <i>Cryptococcus neoformans</i> by Disrupting the GSH Oxidation–Reduction System
Magnolol has fungistatic and fungicidal ability for <i>Cryptococcus neoformans</i> and can inhibit the urease production capacity of <i>Cryptococcus neoformans</i>. The antifungal mechanism of magnolol may be that it disrupts redox homeostasis and inhibits detoxification by affecting Glutathione metabolism.
Authors
- Fenghua Zhang (ORCID: https://orcid.org/0000-0002-5923-2290)
- Tiantian Wang
- Pingchuan Li (ORCID: https://orcid.org/0000-0001-6666-9389)
Institutions
- Shanghai University of Medicine and Health Sciences (CN)
- Taian City Central Hospital (CN)
Publication Details
- Journal
- Canadian Journal of Infectious Diseases and Medical Microbiology
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1155/cjid/8258892
- Citations
- 3
- Primary Topic
- Bioactive Compounds and Antitumor Agents
- Type
- article
- Field-Weighted Citation Impact
- 3.92
Funders
- Shanghai Pudong New Area Health Commission