Evaluating the Antitumor Effect of Root Extract of Salvadora persica in Hepatocarcinoma Through the Induction of Apoptosis via an Intrinsic Pathway: An In Vitro Study
In the present study, <i>Salvadora persica</i> aqueous extract demonstrated dose-dependent antitumor potential in the HCC cell line HepG2 through the induction of intrinsic apoptosis and showed non-toxic activity in the normal hepatic THLE-2 cell line, emphasizing its therapeutic efficacy in HCC treatment.
Authors
- Fouzia Latif
- Mingjing Lu (ORCID: https://orcid.org/0000-0002-5996-1063)
- Kong Qun
Institutions
- Qilu University of Technology (CN)
Publication Details
- Journal
- Cureus
- Published
- 2025-10-04
- DOI
- https://doi.org/10.7759/cureus.93847
- Primary Topic
- Bioactive natural compounds
- Type
- article
- Field-Weighted Citation Impact
- 0.00