Expression of antibody–drug conjugate targets in soft tissue sarcomas
STSs express multiple target genes relevant for ADC treatment and expression varies between and within the pathological types. This comprehensive ADC target landscape, based on the largest molecular epidemiology study in STS, should help clinicians and drug developers for further evaluation of ADCs across STS types.
Authors
- Audrey Monneur
- Jean‐Yves Blay (ORCID: https://orcid.org/0000-0001-7190-120X)
- Émilie Mamessier (ORCID: https://orcid.org/0000-0002-3516-0093)
- M. Brahmi
- Antoîne Italiano (ORCID: https://orcid.org/0000-0002-8540-5351)
- Isabelle Treilleux (ORCID: https://orcid.org/0000-0003-3919-5506)
- Pascal Finetti (ORCID: https://orcid.org/0000-0002-2674-3123)
- Axel Le Cesne (ORCID: https://orcid.org/0000-0002-8006-8659)
- Lénaïg Mescam
- François Bertucci (ORCID: https://orcid.org/0000-0002-0157-0959)
- A Frejafon
Institutions
- Institut Gustave Roussy (FR)
- Centre Léon Bérard (FR)
- Institut Paoli-Calmettes (FR)
Publication Details
- Journal
- ESMO Open
- Published
- 2025-10-01
- DOI
- https://doi.org/10.1016/j.esmoop.2025.105837
- Primary Topic
- Sarcoma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00