Protective efficacy of the UniFluVec influenza vaccine vector against the highly pathogenic influenza A/Indonesia/5/2005 (H5N1) strain in ferrets
The replication-deficient UniFluVec vector demonstrates safety, immunogenicity, and protective efficacy against the heterologous HPAIV strain in ferrets following a single intranasal administration.
Authors
- Boris Ferko
- Julia Romanova
- F Kostolanský
- E Varečková
- Artem Krokhin
- Andrej Egorov (ORCID: https://orcid.org/0000-0003-3883-7677)
- Dirk Pleimes
Institutions
- Silence Therapeutics (Germany) (DE)
- Capricorn Automotive (United Kingdom) (GB)
- Harmonic Drive (Germany) (DE)
- Institute of Virology of the Slovak Academy of Sciences (SK)
- Orano (United States) (US)
Publication Details
- Journal
- Vaccine
- Published
- 2025-10-01
- DOI
- https://doi.org/10.1016/j.vaccine.2025.127795
- Citations
- 2
- Primary Topic
- Influenza Virus Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 2.71