Inverted follicular keratosis of the ear lobe masquerading as malignancy

Inverted follicular keratosis (IFK) is a rare benign tumour of the hair follicle infundibulum, often misdiagnosed as malignancy due to its clinical resemblance to squamous cell carcinoma and basal cell carcinoma. It typically presents as a solitary lesion on the face or neck of elderly individuals. Involvement of ear lobes is a rare occurrence. We report a case of a 66-year-old male who presented with a painful, progressively enlarging nodule on the posterior aspect of the left ear lobe. The lesion was clinically suspected to be squamous cell carcinoma or chondrodermatitis nodularis helicis. Histopathological examination following a punch biopsy confirmed the diagnosis of IFK. The patient was referred for surgical excision, which remains the mainstay of treatment. This case highlights the diagnostic challenge posed by IFK and underscores the importance of histopathology in distinguishing it from malignancies.

Authors

Publication Details

Journal
The Sri Lanka Journal of Dermatology
Published
2025-10-04
DOI
https://doi.org/10.4038/sljd.v24i1.51
Primary Topic
Cancer and Skin Lesions
Type
article
Field-Weighted Citation Impact
0.00
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article

Inverted follicular keratosis of the ear lobe masquerading as malignancy

J. Akarawita, Mohammed Ismail Benazir, Augusto Silva, A. S. Danthanarayana et al.
The Sri Lanka Journal of Dermatology
Cancer and Skin Lesions
article

Inverted follicular keratosis of the ear lobe masquerading as malignancy

J. Akarawita, Mohammed Ismail Benazir, Augusto Silva, A. S. Danthanarayana, N. L. Dinaratne
article en

Abstract

Inverted follicular keratosis (IFK) is a rare benign tumour of the hair follicle infundibulum, often misdiagnosed as malignancy due to its clinical resemblance to squamous cell carcinoma and basal cell carcinoma. It typically presents as a solitary lesion on the face or neck of elderly individuals. Involvement of ear lobes is a rare occurrence. We report a case of a 66-year-old male who presented with a painful, progressively enlarging nodule on the posterior aspect of the left ear lobe. The lesion was clinically suspected to be squamous cell carcinoma or chondrodermatitis nodularis helicis. Histopathological examination following a punch biopsy confirmed the diagnosis of IFK. The patient was referred for surgical excision, which remains the mainstay of treatment. This case highlights the diagnostic challenge posed by IFK and underscores the importance of histopathology in distinguishing it from malignancies.

The Sri Lanka Journal of DermatologyVol. 24(1)
Openalex Percentile: Top 52%
Cancer and Skin Lesions
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Inverted follicular keratosis of the ear lobe masquerading as malignancy — J. Akarawita, Mohammed Ismail Benazir, et al. · The Sri Lanka Journal of Dermatology (2025) | TGRS Research Map | TGRS