Identification of age-group reservoirs for persistent vaccine-type pneumococcal carriage in rural Gambia

In rural Gambia, school-aged children, particularly those aged 5-9 years, are the main drivers of VT pneumococcal transmission. In the context of high coverage of routine PCV vaccination in infants, this suggests waning PCV protection by school entry. A booster dose for children at school entry may support better control of VT circulation in the population.

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Publication Details

Journal
Pneumonia
Published
2025-10-04
DOI
https://doi.org/10.1186/s41479-025-00176-w
Primary Topic
Pneumonia and Respiratory Infections
Type
article
Field-Weighted Citation Impact
0.00
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article

Identification of age-group reservoirs for persistent vaccine-type pneumococcal carriage in rural Gambia

Golam Sarwar, Nuredin Mohammed, Stefan Flasche, Grant Mackenzie et al.
Pneumonia
Pneumonia and Respiratory Infections
article

Identification of age-group reservoirs for persistent vaccine-type pneumococcal carriage in rural Gambia

Golam Sarwar, Nuredin Mohammed, Stefan Flasche, Grant Mackenzie, Kevin van Zandvoort, Rasheed Salaudeen, Ousman Barjo, Minteh Molfa, Isaac Osei, Jane Bruce, Emmanuel Mendy, Brian Greenwood, Olimatou Jobe
article en

Abstract

In rural Gambia, school-aged children, particularly those aged 5-9 years, are the main drivers of VT pneumococcal transmission. In the context of high coverage of routine PCV vaccination in infants, this suggests waning PCV protection by school entry. A booster dose for children at school entry may support better control of VT circulation in the population.

PneumoniaVol. 17(1)
The University of Melbourne (AU), London School of Hygiene & Tropical Medicine (GB), MRC Unit the Gambia (GM), Berlin Institute of Health at Charité - Universitätsmedizin Berlin (DE), Murdoch Children's Research Institute (AU), Charité - Universitätsmedizin Berlin (DE)
Openalex Percentile: Top 63%
Pneumonia and Respiratory Infections
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Identification of age-group reservoirs for persistent vaccine-type pneumococcal carriage in rural Gambia — Golam Sarwar, Nuredin Mohammed, et al. · Pneumonia (2025) | TGRS Research Map | TGRS