Visible Light‐induced Organophotocatalytic Umpolung C(sp <sup>3</sup> )‐H Functionalization of Barbituric Acids
Abstract This study presents a sustainable and efficient visible‐light‐driven organophotocatalytic strategy for transforming the methylene carbon of barbituric acids into valuable hydrazones and spirocyclic products. The reaction proceeds smoothly under mild conditions by utilizing eosin Y as a green photocatalyst and atmospheric oxygen as the sole oxidant. This method provides an environmentally friendly alternative to traditional approaches and offers intriguing mechanistic insights into umpolung C(sp3)‐H functionalization, thereby paving the way for novel reactivity in barbiturate chemistry.
Authors
- Mohit L. Deb
- Jayanta Kr. Nath (ORCID: https://orcid.org/0000-0002-0477-5861)
- Pranjal K. Baruah (ORCID: https://orcid.org/0000-0002-5829-1440)
- Priyanka Nath
Institutions
- Gauhati University (IN)
- University of Science and Technology, Meghalaya (IN)
- National Law University and Judicial Academy (IN)
Publication Details
- Journal
- Asian Journal of Organic Chemistry
- Published
- 2025-10-04
- DOI
- https://doi.org/10.1002/ajoc.70226
- Primary Topic
- Radical Photochemical Reactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00