Evaluation of the prognostic value of centrosome-related genes and assessment of the immune microenvironment in osteosarcoma

We developed and validated a novel CRG-based prognostic score demonstrating potential clinical utility for OS outcome prediction. This molecular score provides mechanistic insights into tumor-immune interactions and offers clinicians a quantitative framework for personalized therapeutic decision-making.

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Publication Details

Journal
Biochemical and Biophysical Research Communications
Published
2025-10-01
DOI
https://doi.org/10.1016/j.bbrc.2025.152739
Primary Topic
RNA modifications and cancer
Type
article
Field-Weighted Citation Impact
0.00
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article

Evaluation of the prognostic value of centrosome-related genes and assessment of the immune microenvironment in osteosarcoma

Hui Yu, Yue Huang, Guoming Xia, Song Luo et al.
Biochemical and Biophysical Research Communications
RNA modifications and cancer
article

Evaluation of the prognostic value of centrosome-related genes and assessment of the immune microenvironment in osteosarcoma

Hui Yu, Yue Huang, Guoming Xia, Song Luo, B. A. Long, Jian‐Hui Liang
article en

Abstract

We developed and validated a novel CRG-based prognostic score demonstrating potential clinical utility for OS outcome prediction. This molecular score provides mechanistic insights into tumor-immune interactions and offers clinicians a quantitative framework for personalized therapeutic decision-making.

Biochemical and Biophysical Research CommunicationsVol. 786
Nanchang University (CN), Second Hospital of Nanchang (CN), First Affiliated Hospital of Nanchang University (CN), Anyang Hospital of Traditional Chinese Medicine (CN)
Openalex Percentile: Top 76%
RNA modifications and cancer
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