Idiopathic Full Thickness Macular Holes: Classification and Current Management Approaches

Idiopathic, full-thickness macular holes (iFTMH) are foveal defects involving all neuroretinal layers, accounting for 85% of macular holes. They arise from age-related vitreous changes causing vitreomacular traction and subsequent hole formation, with peak incidence between the ages 60 to 70, and a 2-3 times greater incidence in women. Symptoms include blurred vision, decreased visual acuity, metamorphopsia or central scotoma. Prompt identification is crucial to ensure appropriate management, as although a minority of cases resolve spontaneously, timely surgical intervention remains the mainstay of treatment to restore anatomy and optimise visual function (4). Advances in vitreoretinal surgery, including pars plana vitrectomy (PPV) with internal limiting membrane (ILM) peeling and emerging techniques such as inverted ILM flaps having improved closure rates, even for chronic or large holes. This review provides a concise overview of the diagnosis, classification and management of iFTMHs.

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Publication Details

Journal
Journal of the Foundations of Ophthalmology
Published
2025-10-04
DOI
https://doi.org/10.48089/jfo7688313
Primary Topic
Retinal and Macular Surgery
Type
article
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article

Idiopathic Full Thickness Macular Holes: Classification and Current Management Approaches

Shruthi Mankal
Journal of the Foundations of Ophthalmology
Retinal and Macular Surgery
article

Idiopathic Full Thickness Macular Holes: Classification and Current Management Approaches

Shruthi Mankal
article en

Abstract

Idiopathic, full-thickness macular holes (iFTMH) are foveal defects involving all neuroretinal layers, accounting for 85% of macular holes. They arise from age-related vitreous changes causing vitreomacular traction and subsequent hole formation, with peak incidence between the ages 60 to 70, and a 2-3 times greater incidence in women. Symptoms include blurred vision, decreased visual acuity, metamorphopsia or central scotoma. Prompt identification is crucial to ensure appropriate management, as although a minority of cases resolve spontaneously, timely surgical intervention remains the mainstay of treatment to restore anatomy and optimise visual function (4). Advances in vitreoretinal surgery, including pars plana vitrectomy (PPV) with internal limiting membrane (ILM) peeling and emerging techniques such as inverted ILM flaps having improved closure rates, even for chronic or large holes. This review provides a concise overview of the diagnosis, classification and management of iFTMHs.

Journal of the Foundations of Ophthalmology
Openalex Percentile: Top 59%
Retinal and Macular Surgery
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Idiopathic Full Thickness Macular Holes: Classification and Current Management Approaches — Shruthi Mankal · Journal of the Foundations of Ophthalmology (2025) | TGRS Research Map | TGRS