Diagnostic Challenges of Thyrotoxicosis in Pregnancy Presenting as Stroke and Hyperemesis Gravidarum

Hyperthyroidism in pregnancy carries serious risks for both the pregnant individual and the fetus. Presenting symptoms may include fatigue, nausea, and palpitations. Timely diagnosis and intervention are challenging because clinical features overlap with physiological changes in pregnancy. This case report describes a diagnostically challenging presentation of thyrotoxicosis in pregnancy with neurological symptoms mimicking a stroke, which is atypical since stroke-like presentations are not typically associated with hyperthyroidism. This case highlights the importance of maintaining a broad differential in pregnant individuals with persistent, unexplained systemic symptoms.

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Publication Details

Journal
Cureus
Published
2025-10-04
DOI
https://doi.org/10.7759/cureus.93831
Primary Topic
Thyroid Disorders and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Diagnostic Challenges of Thyrotoxicosis in Pregnancy Presenting as Stroke and Hyperemesis Gravidarum

Jahangir Rouzbehani, Fatima Kamal, Kathy Kamath, Varsha Pudi
Cureus
Thyroid Disorders and Treatments
article

Diagnostic Challenges of Thyrotoxicosis in Pregnancy Presenting as Stroke and Hyperemesis Gravidarum

Jahangir Rouzbehani, Fatima Kamal, Kathy Kamath, Varsha Pudi
article en

Abstract

Hyperthyroidism in pregnancy carries serious risks for both the pregnant individual and the fetus. Presenting symptoms may include fatigue, nausea, and palpitations. Timely diagnosis and intervention are challenging because clinical features overlap with physiological changes in pregnancy. This case report describes a diagnostically challenging presentation of thyrotoxicosis in pregnancy with neurological symptoms mimicking a stroke, which is atypical since stroke-like presentations are not typically associated with hyperthyroidism. This case highlights the importance of maintaining a broad differential in pregnant individuals with persistent, unexplained systemic symptoms.

CureusVol. 17(10)
University of Vermont (US), Danbury Hospital (US)
Openalex Percentile: Top 63%
Thyroid Disorders and Treatments
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