Sedative and hemodynamic effects of clonidine in mechanically ventilated adult patients: a population pharmacodynamic study
Purpose The aim of this study was to characterize the the effects of clonidine on sedation, heart rate (HR) and mean arterial blood pressure (MAP) in critically ill, mechanically ventilated adult patients, using population pharmacodynamic modelling. M
Authors
- Maurits Arbouw
- Ron A. A. Mathôt (ORCID: https://orcid.org/0000-0001-8401-0879)
- Arriette Kruisdijk‐Gerritsen
- Marieke Zeeman
- Polina Nassikovker
- Arthur R. de Meijer
- Michael E. Cloesmeijer (ORCID: https://orcid.org/0000-0002-2810-1570)
- Huub L.A. van den Oever (ORCID: https://orcid.org/0000-0001-6621-8940)
- Carmen M.A. Bles
- Fred L. van Steveninck
Institutions
- Amsterdam University Medical Centers (NL)
- Deventer Ziekenhuis (NL)
Publication Details
- Published
- 2025-10-04
- DOI
- https://doi.org/10.22541/au.175958121.16015162/v1
- Primary Topic
- Anesthesia and Sedative Agents
- Type
- article
- Field-Weighted Citation Impact
- 0.00