Visible‐Light‐Promoted Cascade Acylmethylation/Annulation of <i>N</i> ‐Alkene‐Linked Indoles with Sulfoxonium Ylides: Synthesis of Acylmethylated Pyrrolo[1,2‐ <i>a</i> ]indoles
A visible‐light‐promoted sequential radical acylmethylation/annulation of unactivated alkenes with sulfoxonium ylides has been developed, furnishing a range of acylmethylated pyrrolo[1,2‐ a ]indoles in high efficiency under photoredox conditions. Notably, this reaction is characterized by mild conditions, operational simplicity, a wide substrate scope, and excellent functional group tolerance.
Authors
- Hongni Qin
- Fan Wu (ORCID: https://orcid.org/0000-0001-7686-2887)
- Yuzhen Xie
- Yong Zhang (ORCID: https://orcid.org/0000-0003-0397-7143)
- Song Sun (ORCID: https://orcid.org/0000-0002-9974-6456)
Institutions
- Changzhou University (CN)
- Suzhou Industrial Park Institute of Services Outsourcing (CN)
Publication Details
- Journal
- European Journal of Organic Chemistry
- Published
- 2025-10-04
- DOI
- https://doi.org/10.1002/ejoc.202500619
- Citations
- 1
- Primary Topic
- Catalytic C–H Functionalization Methods
- Type
- article
- Field-Weighted Citation Impact
- 0.94