Vision and Quality of Life in Fuchs’ Endothelial Dystrophy Using a Prototype Aberrometer: A Cross-Sectional Study

Worse-eye BDCVA correlates with patient-reported quality of life in FECD; however, adding high-resolution optical metrics (eg, wavefront/HPFM) did not meaningfully improve explanatory or predictive performance beyond simple clinical variables. These findings highlight a current gap: advanced optical metrics are not yet sufficient to reliably predict the subjective patient experience. Any conclusions from this study should be considered highly preliminary pending confirmation by further research.

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Publication Details

Journal
Clinical ophthalmology
Published
2025-10-01
DOI
https://doi.org/10.2147/opth.s548402
Primary Topic
Corneal surgery and disorders
Type
article
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article

Vision and Quality of Life in Fuchs’ Endothelial Dystrophy Using a Prototype Aberrometer: A Cross-Sectional Study

Miriam Velasco‐Ocaña, Ignacio Mahíllo, Nicolás Alejandre‐Alba, Ignacio Jiménez-Alfaro et al.
Clinical ophthalmology
Corneal surgery and disorders
article

Vision and Quality of Life in Fuchs’ Endothelial Dystrophy Using a Prototype Aberrometer: A Cross-Sectional Study

Miriam Velasco‐Ocaña, Ignacio Mahíllo, Nicolás Alejandre‐Alba, Ignacio Jiménez-Alfaro, Vito Romano, José G. Marichal-Hernández, Gonzalo Velarde‐Rodríguez, Carolina Belda-Para, Katrin Wacker, José Manuel Rodríguez-Ramos
article en

Abstract

Worse-eye BDCVA correlates with patient-reported quality of life in FECD; however, adding high-resolution optical metrics (eg, wavefront/HPFM) did not meaningfully improve explanatory or predictive performance beyond simple clinical variables. These findings highlight a current gap: advanced optical metrics are not yet sufficient to reliably predict the subjective patient experience. Any conclusions from this study should be considered highly preliminary pending confirmation by further research.

Clinical ophthalmologyVol. Volume 19
Universidad de La Laguna (ES), University of Freiburg (DE), Surgical Specialties (Canada) (CA), Hospital Universitario Fundación Jiménez Díaz (ES), University of Brescia (IT)
Openalex Percentile: Top 59%
Corneal surgery and disorders
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Vision and Quality of Life in Fuchs’ Endothelial Dystrophy Using a Prototype Aberrometer: A Cross-Sectional Study — Miriam Velasco‐Ocaña, Ignacio Mahíllo, et al. · Clinical ophthalmology (2025) | TGRS Research Map | TGRS