Preoperative staging of cervical cancer: time to shift from cystoscopy to MRI
Question The prognostic significance of MRI-defined bladder wall invasion in patients with cervical cancer remains unclear with respect to disease recurrence and survival. Findings Bladder wall invasion identified on MRI is an independent predictor of tumor recurrence and tumor-specific mortality, whereas mucosal infiltration detected via cystoscopy is not. Clinical relevance MRI can safely replace cystoscopy in the preoperative staging of patients with uterine cervical cancer. This approach can reduce costs and expedite the staging process.
Authors
- Benedetta Gui (ORCID: https://orcid.org/0000-0002-5130-2100)
- Miriam Dolciami (ORCID: https://orcid.org/0000-0002-8322-8435)
- Sara Notaro (ORCID: https://orcid.org/0000-0002-7672-8861)
- Vincenzo Vingiani
- Matteo Bonatti (ORCID: https://orcid.org/0000-0002-4477-8944)
- Giacomo Avesani (ORCID: https://orcid.org/0000-0001-9926-760X)
- Evis Sala (ORCID: https://orcid.org/0000-0002-5518-9360)
- Riccardo Valletta (ORCID: https://orcid.org/0000-0003-3465-0151)
- Nicolò Bizzarri (ORCID: https://orcid.org/0000-0002-1727-904X)
- Luca D’Erme
- Martin Steinkasserer
- Giovanni Negri (ORCID: https://orcid.org/0000-0002-9194-8782)
- Francesca Vanzo
- Elena Magri
- Chiara Innocenzi (ORCID: https://orcid.org/0009-0001-6997-9099)
- Roberta Chianura
- Pietro Paolo Maria Azzaro
Institutions
- Università Cattolica del Sacro Cuore (IT)
- University of Trento (IT)
- Agostino Gemelli University Polyclinic (IT)
- Ospedale di Bolzano (IT)
- Provincia Autonoma di Trento (IT)
- University of the Sacred Heart (JP)
Publication Details
- Journal
- European Radiology
- Published
- 2025-10-04
- DOI
- https://doi.org/10.1007/s00330-025-12039-5
- Primary Topic
- Endometrial and Cervical Cancer Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00