The relationship between gut microbiota, plasma metabolites, and iron deficiency anemia in European populations: a three-sample Mendelian randomization analysis

Our findings validate the crucial role of gut microbiota in IDA etiology, highlighting mediation via key plasma metabolites. These insights enhance understanding of the gut microbiota-hematopoiesis axis and offer potential avenues for novel biomarkers or therapeutic interventions targeting IDA.

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Publication Details

Journal
Hematology
Published
2025-10-04
DOI
https://doi.org/10.1080/16078454.2025.2549962
Primary Topic
Genetic Associations and Epidemiology
Type
article
Field-Weighted Citation Impact
0.00
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article

The relationship between gut microbiota, plasma metabolites, and iron deficiency anemia in European populations: a three-sample Mendelian randomization analysis

Jun Yin, Xuwen Zheng, Wenming Shen
Hematology
Genetic Associations and Epidemiology
article

The relationship between gut microbiota, plasma metabolites, and iron deficiency anemia in European populations: a three-sample Mendelian randomization analysis

Jun Yin, Xuwen Zheng, Wenming Shen
article en

Abstract

Our findings validate the crucial role of gut microbiota in IDA etiology, highlighting mediation via key plasma metabolites. These insights enhance understanding of the gut microbiota-hematopoiesis axis and offer potential avenues for novel biomarkers or therapeutic interventions targeting IDA.

HematologyVol. 30(1)
Xuzhou Medical College (CN)
Openalex Percentile: Top 71%
Genetic Associations and Epidemiology
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