Cervical Spinal Cord Metastasis of Germ Cell Tumor: A Rare Case Report

Malignant germ cell tumors (GCTs) spreading to the central nervous system (CNS) are uncommon, particularly when it comes to spinal cord metastases, which are extremely rare. This report details a case involving a metastatic cervical spinal cord GCT in a patient who had previously been diagnosed with a primary malignant GCT of the right testicle 3 years earlier. The patient experienced progressive cervical pain, and imaging revealed a mass in the cervical spinal cord area. Histopathological analysis confirmed that the mass was a malignant GCT, indicating it was a metastatic spread from the original testicular tumor. This case underscores the rarity of spinal cord metastases resulting from GCTs and emphasizes the necessity of considering metastatic disease in patients with a history of GCTs when they present with neurological symptoms (as often the earliest and most common presenting features).

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Publication Details

Journal
Clinical Case Reports
Published
2025-10-01
DOI
https://doi.org/10.1002/ccr3.71081
Primary Topic
Testicular diseases and treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Cervical Spinal Cord Metastasis of Germ Cell Tumor: A Rare Case Report

Elaheh Farmani, Behnoud Vesali, Elham Nazar, Aysan Nozheh et al.
Clinical Case Reports
Testicular diseases and treatments
article

Cervical Spinal Cord Metastasis of Germ Cell Tumor: A Rare Case Report

Elaheh Farmani, Behnoud Vesali, Elham Nazar, Aysan Nozheh, Aida Tarighi
article en

Abstract

Malignant germ cell tumors (GCTs) spreading to the central nervous system (CNS) are uncommon, particularly when it comes to spinal cord metastases, which are extremely rare. This report details a case involving a metastatic cervical spinal cord GCT in a patient who had previously been diagnosed with a primary malignant GCT of the right testicle 3 years earlier. The patient experienced progressive cervical pain, and imaging revealed a mass in the cervical spinal cord area. Histopathological analysis confirmed that the mass was a malignant GCT, indicating it was a metastatic spread from the original testicular tumor. This case underscores the rarity of spinal cord metastases resulting from GCTs and emphasizes the necessity of considering metastatic disease in patients with a history of GCTs when they present with neurological symptoms (as often the earliest and most common presenting features).

Clinical Case ReportsVol. 13(10)
Sina Hospital (IR), Tehran University of Medical Sciences (IR)
Openalex Percentile: Top 56%
Testicular diseases and treatments
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