Lycium barbarum Polysaccharides Suppress Radiation-Induced Microglial Inflammation by Inhibiting the IKKβ/IκBα/NF-κB Pathway
Our findings demonstrate that LBP mitigates radiation-induced microglial inflammation by inhibiting the IKKβ/IκBα/NF-κB pathway, suggesting its potential as a radioprotective agent against radiotherapy-induced neuroinflammation.
Authors
- Qun Liu (ORCID: https://orcid.org/0000-0003-2022-117X)
- Feng Ru Tang (ORCID: https://orcid.org/0000-0003-2462-1787)
- Feng Qian (ORCID: https://orcid.org/0000-0001-5766-4623)
- Lian Liu (ORCID: https://orcid.org/0000-0001-6489-227X)
- Xing Zhang (ORCID: https://orcid.org/0000-0002-5877-627X)
- Bo Ren
Institutions
- National University of Singapore (SG)
- Yangtze University (CN)
- Wuhan City Chinese Medicine Hospital (CN)
- Wuhan No.1 Hospital (CN)
Publication Details
- Journal
- Dose-Response
- Published
- 2025-10-01
- DOI
- https://doi.org/10.1177/15593258251382964
- Citations
- 2
- Primary Topic
- Neuroinflammation and Neurodegeneration Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 1.68