Optimizing latency calculation for robust evaluation of the pupillary light response in chromatic pupillography

The use of the intersection of a linear fit through the baseline with a linear fit containing an adjusted number of data points adapted to the characteristics of the pupillary contraction phase appears to be suitable to provide consistent latency calculation, particularly for small constriction amplitudes and noisy data as they may occur in patients with e.g. hereditary retinal degenerations. The evaluation of mean latency per eccentricity is equivalent and may be advantageous in difficult clinical test results with low amplitudes.

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Publication Details

Journal
Documenta Ophthalmologica
Published
2025-10-04
DOI
https://doi.org/10.1007/s10633-025-10055-w
Primary Topic
Glaucoma and retinal disorders
Type
article
Field-Weighted Citation Impact
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article

Optimizing latency calculation for robust evaluation of the pupillary light response in chromatic pupillography

Ronja Jung, Torsten Straßer, Ricarda Jendritza, Helmut Wilhelm et al.
Documenta Ophthalmologica
Glaucoma and retinal disorders
article

Optimizing latency calculation for robust evaluation of the pupillary light response in chromatic pupillography

Ronja Jung, Torsten Straßer, Ricarda Jendritza, Helmut Wilhelm, Carina Kelbsch, Barbara Wilhelm, Anton Sonntag, Márton Edelmayer, Tobias Peters
article en

Abstract

The use of the intersection of a linear fit through the baseline with a linear fit containing an adjusted number of data points adapted to the characteristics of the pupillary contraction phase appears to be suitable to provide consistent latency calculation, particularly for small constriction amplitudes and noisy data as they may occur in patients with e.g. hereditary retinal degenerations. The evaluation of mean latency per eccentricity is equivalent and may be advantageous in difficult clinical test results with low amplitudes.

Documenta Ophthalmologica
STZ eyetrial (DE), University of Tübingen (DE)
Openalex Percentile: Top 59%
Glaucoma and retinal disorders
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