Bloomy Rind Sign in Leptomeningeal Metastasis of Primary Lung Adenocarcinoma
The bloomy rind sign, which appears as hyperintensities on FLAIR along the surface of the brainstem without gadolinium contrast enhancement, is a rare and early finding indicative of leptomeningeal metastasis in patients with lung adenocarcinoma, often associated with EGFR gene mutations.
Authors
- Wenyuan Tao (ORCID: https://orcid.org/0000-0001-9047-4231)
- Xinhua Chen (ORCID: https://orcid.org/0000-0002-4573-9111)
- L. Han (ORCID: https://orcid.org/0009-0000-1534-6336)
- Xin Zhang (ORCID: https://orcid.org/0000-0003-0047-3134)
Institutions
- Nanjing Drum Tower Hospital (CN)
Publication Details
- Journal
- Clinical Case Reports
- Published
- 2025-10-01
- DOI
- https://doi.org/10.1002/ccr3.71151
- Primary Topic
- Brain Metastases and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China