Promethazine Combined with Metoclopramide for the Prevention of Postoperative Nausea and Vomiting in Patients Undergoing Laparoscopic Colorectal Cancer Surgery: A Randomized Controlled Trial
Preoperative prophylactic promethazine significantly reduced the incidence and severity of PONV within 24 hours postoperatively, with few adverse effects and no serious adverse reactions. Additionally, patient satisfaction was also improved.
Authors
- Bin Tian (ORCID: https://orcid.org/0000-0002-5116-027X)
- Jiqiang Zhang (ORCID: https://orcid.org/0000-0002-1905-8750)
- Xia Li (ORCID: https://orcid.org/0000-0003-1445-708X)
- Ruijuan Liu (ORCID: https://orcid.org/0000-0001-8445-8470)
- Wenjun Yan (ORCID: https://orcid.org/0000-0003-1938-1782)
- Ruirui Bi
Institutions
- Nanjing Drum Tower Hospital (CN)
- Gansu Provincial Hospital (CN)
- First Affiliated Hospital of Zhengzhou University (CN)
Publication Details
- Journal
- Drug Design Development and Therapy
- Published
- 2025-10-01
- DOI
- https://doi.org/10.2147/dddt.s526724
- Primary Topic
- Nausea and vomiting management
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Lanzhou Science and Technology Bureau