Salmonella typhimurium downregulates circHIPK2 expression via CeRNA mechanism to inhibit cell migration and tumorigenesis
The S. typhimurium-regulated circHIPK2/miR-124-3p axis is pivotal in CRC pathogenesis and holds promise as a molecular therapeutic target for treating colitis-associated colorectal cancer.
Authors
- Xiaoting Luan
- Minyi Chen (ORCID: https://orcid.org/0000-0002-9299-5353)
- Yuyu Xu
- Xiaoyi Wang (ORCID: https://orcid.org/0000-0001-5766-0876)
- Fei Wang (ORCID: https://orcid.org/0000-0002-4146-5379)
- Huihui Ma
Institutions
- Jiangnan University (CN)
- Southern University of Science and Technology (CN)
- Ministry of Education (KR)
- Wuxi Fourth People's Hospital (CN)
- Jiangxi Mental Health Center (CN)
Publication Details
- Journal
- Gut Pathogens
- Published
- 2025-10-04
- DOI
- https://doi.org/10.1186/s13099-025-00759-4
- Primary Topic
- Circular RNAs in diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Wuxi Municipal Bureau on Science and Technology