Evaluation of the effects of antiepileptic monotherapy on pubertal hormones in adolescent girls with epilepsy
VPA appears to negatively impact thyroid and adrenal hormones in adolescent girls, whereas LEV has a safer endocrine profile. Given the hormonal sensitivity during puberty, LEV may be a safer alternative for adolescent girls with epilepsy to reduce potential endocrine disturbances.
Authors
- Zeynep Selen Karalök (ORCID: https://orcid.org/0000-0001-5465-7380)
- Altan Güneş (ORCID: https://orcid.org/0000-0002-0365-1218)
- Murat Kızılgün (ORCID: https://orcid.org/0000-0001-5551-4058)
- Ali Nazım Güzelbağ (ORCID: https://orcid.org/0000-0003-3314-9090)
- Pınar Kocaay (ORCID: https://orcid.org/0000-0003-0850-0360)
- Alkım Öden Akman (ORCID: https://orcid.org/0000-0001-8080-7127)
- Berivan Güzelbağ (ORCID: https://orcid.org/0000-0002-1141-6381)
Institutions
- Haseki Eğitim ve Araştırma Hastanesi (TR)
- Istinye University (TR)
- Sağlık Bilimleri Üniversitesi (TR)
- Kent Hastanesi (TR)
- Gaziosmanpaşa Taksim Eğitim ve Araştırma Hastanesi (TR)
Publication Details
- Journal
- Pediatrics International
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1111/ped.70209
- Primary Topic
- Pharmacological Effects and Toxicity Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00